Browsing Department of Biology, Chemistry and Environmental Sciences by Author "6aa0c2ce-db72-4613-95e5-202607b82cf8"
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Antiamoebic activity of plant‑based natural products and their conjugated silver nanoparticles against Acanthamoeba castellanii (ATCC 50492)
Anwar, Areeba; Ting, Elaine Lim Siew; Anwar, Ayaz; Ain, Noor ul; Faizi, Shaheen; Shah, Muhammad Raza; Khan, Naveed; Siddiqui, Ruqaiyyah (Springer, 2020)Acanthamoeba spp. are the causative agent of Acanthamoeba keratitis and granulomatous amoebic encephalitis (GAE). The current options to treat Acanthamoeba infections have limited success. Silver nanoparticles show ... -
Isoniazid Conjugated Magnetic Nanoparticles Loaded with Amphotericin B as a Potent Antiamoebic Agent against Acanthamoeba castellanii
Iqbal, Kawish; Abdelnasir, Sumayah; Anwar, Ayaz; Iqbal, Kanwal Muhammad; Shah, Muhammad Raza; Anwar, Areeba; Siddiqui, Ruqaiyyah; Khan, Naveed (MDPI, 2020)The pathogenic free-living amoeba, Acanthamoeba castellanii, is responsible for a rare but deadly central nervous system infection, granulomatous amoebic encephalitis and a blinding eye disease called Acanthamoeba keratitis. ... -
Metronidazole conjugated magnetic nanoparticles loaded with amphotericin B exhibited potent effects against pathogenic Acanthamoeba castellanii belonging to the T4 genotype
Abdelnasir, Sumayah; Anwar, Ayaz; Kawish, Muhammad; Anwar, Areeba; Shah, Muhammad Raza; Siddiqui, Ruqaiyyah; Khan, Naveed (Springer, 2020)Acanthamoeba castellanii can cause granulomatous amoebic encephalitis and Acanthamoeba keratitis. Currently, no single drug has been developed to effectively treat infections caused by Acanthamoeba. Recent studies have ... -
Transcriptome analysis of Escherichia coli K1 after therapy with hesperidin conjugated with silver nanoparticles
Masri, Abdulkader; Khan, Naveed; Zoqratt, Muhammad Zarul Hanifah Md; Ayub, Qasim; Anwar, Ayaz; Rao, Komal; Shah, Muhammad Raza; Siddiqui, Ruqaiyyah (BioMed Central Ltd, 2021)Backgrounds: Escherichia coli K1 causes neonatal meningitis. Transcriptome studies are indispensable to comprehend the pathology and biology of these bacteria. Recently, we showed that nanoparticles loaded with Hesperidin ...