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Analysis of 5-chloro-8-methoxy-2-(bromomethyl)quinoline by XPS
(American Vacuum Society, 2004)
Macrocyclic ethers are used extensively for their ability to form strong and selective interactions with charged species. It has been shown that the incorporation of heterocyclic groups into macrocylclic ethers increase ...
The use of ultrasound to release chemotherapeutic drugs from micelles and liposomes
(Taylor & Francis, 2014)
Several drug delivery systems have been investigated to reduce the side effects of chemotherapy by encapsulating the therapeutic agent in a nanosized carrier until it reaches the tumor site. Many of these particles are ...
Preliminary Modeling of Transfer RNA Kinetics in the Cytoplasm of Escherichia coli Bacteria
(American Scientific Publishers, 2010)
Transfer RNAs (tRNAs) can recognize a specific amino acid from a possible pool of 20. Theyare able to transport these protein building-blocks to the ribosome, the site where amino acids assemble into protein chains. Accurate ...
Possible Physical Mechanisms of tRNA Pre-Selection in the Cytoplasm of Escherichia coli Bacteria
(American Scientific Publishers, 2010)
In a previous publication, we used kinetic models to simulate the physical movement ofthe transfer RNA (tRNA) in the cytoplasm of Escherichia coli and concluded that tRNA molecules are not able to approach the ribosome by ...
Carbohydrate-Functionalized Liposomes In Cancer Therapy
(Bentham Science, 2020)
Existing cancer treatments are often accompanied by adverse side effects that can greatly reduce the quality of life of cancer patients; this sets the platform for the development and application of nanocarrier-based ...
Ultrasound-Mediated Drug Delivery in Cancer Therapy: A Review
(American Scientific Publishers, 2020)
The use of ultrasound as a medical diagnostic tool began in the 1940s. Ever since, the medical applications of ultrasound have included imaging, tumor ablation, and lithotripsy; however, an ever-increasing body of literature ...
Ultrasound-induced doxorubicin release from folate-targeted and non-targeted P105 micelles: a modeling study
(De Gruyter, 2016)
The aim of this work is to study the kinetics of ultrasound (70 kHz) – using a kinetic model that takes into account cavitation events and drug re-encapsulation upon the cessation of the acoustic field. The simulation ...
Identification of the Uncertainty Structure to Estimate the Acoustic Release of Chemotherapeutics From Polymeric Micelles
(IEEE, 2017)
This paper estimates the acoustic drug release from micelles after accurately identifying the underlying statistical noise characteristics in experimental data. The drug release is measured as a change in fluorescence as ...
Investigating the Release Mechanism of Calcein from eLiposomes at Higher Temperatures
(American Scientific Publishers, 2014)
Numerous nanocarriers are currently being investigated as drug delivery vehicles for transporting chemotherapeutics to cancer cells. Our research group has recently synthesized a new generation of echogenic liposomes based ...
Recent Advances in Metal-Organic Frameworks as Anticancer Drug Delivery Systems: A Review
(Bentham, 2021)
Background: Metal-organic frameworks (MOFs), as attractive hybrid crystalline porous materials, are increasingly being investigated in biomedical applications owing to their exceptional properties, including high porosity, ...