Browsing Department of Chemical and Biological Engineering by Subject "Cancer"
Now showing items 1-16 of 16
-
Anti-cancer Drug Delivery Using Metal Organic Frameworks (MOFs)
(Bentham Science Publishers, 2017)Cancer is the uncontrolled growth of cells in the body and is considered as one of the major causes of death globally. There are several cytotoxic chemotherapeutic agents used to treat cancer including methotrexate, ... -
Carbohydrate-Functionalized Liposomes In Cancer Therapy
(Bentham Science, 2020)Existing cancer treatments are often accompanied by adverse side effects that can greatly reduce the quality of life of cancer patients; this sets the platform for the development and application of nanocarrier-based ... -
Drug Delivery Systems Based on Polymeric Micelles and Ultrasound: A Review
(Bentham Science Publishers, 2016)Anti-neoplastic drugs used for cancer treatment often produce damage to healthy cells, leading to severe side effects in patients undergoing chemotherapy. The encapsulation of these agents in nanoparticles reduces the ... -
Dual-Targeting and Stimuli-Triggered Liposomal Drug Delivery in Cancer Treatment
(American Chemical Society, 2021)The delivery of chemotherapeutics to solid tumors using smart drug delivery systems (SDDSs) takes advantage of the unique physiology of tumors (i.e., disordered structure, leaky vasculature, abnormal extracellular matrix ... -
Effect of phospholipid head group on ultrasound‑triggered drug release and cellular uptake of immunoliposomes
(Nature, 2023)Liposomes are the most successful nanoparticles used to date to load and deliver chemotherapeutic agents to cancer cells. They are nano-sized vesicles made up of phospholipids, and targeting moieties can be added to their ... -
Immunoliposomes: Synthesis, Structure, and Their Potential as Drug Delivery Carriers
(Bentham Science, 2020)Immunoliposomes have emerged as attractive drug targeting vehicles for cancer treatment. This review presents the recent advances in the design of immunoliposomes encapsulating a variety of chemotherapeutic agents. We ... -
Liposomes as a Promising Ultrasound-Triggered Drug Delivery System in Cancer Treatment
(Bentham Science, 2017)The initial uses of ultrasound waves in the medical field were limited to the thermal ablation of solid tumors and as a diagnostic tool. Recent advances at the preclinical stage have allowed the use of ultrasound as a ... -
Modeling the Effects of Chemotherapy and Immunotherapy on Tumor Growth
(American Scientific Publishers, 2021)Mathematical modeling has been used to simulate the interaction of chemotherapy and immunotherapy drugs intervention with the dynamics of tumor cells growth. This work studies the interaction of cells in the immune system, ... -
Multi-Model Investigation and Adaptive Estimation of the Acoustic Release of a Model Drug From Liposomes
(IEEE, 2019)This paper researches a suitable mathematical model that can reliably predict the release of a model drug (namely calcein) from biologically targeted liposomal nanocarriers triggered by ultrasound. Using mathematical models, ... -
pH-Responsive Nanocarriers in Cancer Therapy
(MDPI, 2022)A number of promising nano-sized particles (nanoparticles) have been developed to conquer the limitations of conventional chemotherapy. One of the most promising methods is stimuli-responsive nanoparticles because they ... -
Transferrin-Targeted Liposomes in Glioblastoma Therapy: A Review
(MDPI, 2026-08-26)Glioblastoma (GBM) is a highly aggressive brain tumor, and its treatment is further complicated by the high selectivity of the blood–brain barrier (BBB). The scientific community is urgently seeking innovative and effective ... -
Ultrasonic-Activated Micellar Drug Delivery for Cancer Treatment
(Wiley InterSciences, 2008)The use of nanoparticles and ultrasound in medicine continues to evolve. Great strides have been made in the areas of producing micelles, nanoemulsions, and solid nanoparticles that can be used in drug delivery. An effective ... -
Ultrasound-sensitive cRGD-modified liposomes as a novel drug delivery system
(Taylor & Francis, 2022)Targeted liposomes enable the delivery of encapsulated chemotherapeutics to tumours by targeting specific receptors overexpressed on the surfaces of cancer cells; this helps in reducing the systemic side effects associated ... -
Ultrasound-triggered Immunotherapy for Cancer Treatment: An Update
(Bentham, 2021) -
Use of Model Predictive Control and Artificial Neural Networks to Optimize the Ultrasonic Release of a Model Drug From Liposomes
(IEEE, 2017)The use of echogenic liposomes to deliver chemotherapeutic agents for cancer treatment has gained wide recognition in the last 20 years. Cancerous cells can develop multiple drug resistance (MDR), in part, due to the drop ... -
The Use of Ultrasound and Micelles in Cancer Treatment
(American Scientific Publishers, 2008)The high toxicity of potent chemotherapeutic drugs like Doxorubicin (Dox) limits the therapeutic window in which they can be applied. This window can be expanded by controlling the drug delivery in both space and time such ...
