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Predicting the Release of Chemotherapeutics From the Core of Polymeric Micelles Using Ultrasound
(IEEE Explore, 2015)
In this paper, the estimation of acoustic drug release from micelles is addressed. The release is measured as a decrease in fluorescence once ultrasound is applied. Initially, a Kalman filter is used to fuse the drug ...
Gas Phase Deposition of Trichloro(1H,1H,2H,2H-perfluorooctyl)silane on Silicon Dioxide, by XPS
(American Vacuum Society, 2012)
Monolayers of trichloro(lH,1H,2H,2H-perfluorooctyl)silane, Cl3SiCH2CH2(CF2)5CF3, were deposited via chemical vapor deposition onto the native oxide layer on silicon after plasma-cleaning. The samples have high hydrophobicity, ...
Rapid separation of very low concentrations of bacteria from blood
(Elsevier, 2017)
A rapid and accurate diagnosis of the species and antibiotic resistance of bacteria in septic blood is vital to increase survival rates of patients with bloodstream infections, particularly those with carbapenem-resistant ...
The use of ultrasound to release chemotherapeutic drugs from micelles and liposomes
(Taylor & Francis, 2014)
Several drug delivery systems have been investigated to reduce the side effects of chemotherapy by encapsulating the therapeutic agent in a nanosized carrier until it reaches the tumor site. Many of these particles are ...
Preliminary Modeling of Transfer RNA Kinetics in the Cytoplasm of Escherichia coli Bacteria
(American Scientific Publishers, 2010)
Transfer RNAs (tRNAs) can recognize a specific amino acid from a possible pool of 20. Theyare able to transport these protein building-blocks to the ribosome, the site where amino acids assemble into protein chains. Accurate ...
Possible Physical Mechanisms of tRNA Pre-Selection in the Cytoplasm of Escherichia coli Bacteria
(American Scientific Publishers, 2010)
In a previous publication, we used kinetic models to simulate the physical movement ofthe transfer RNA (tRNA) in the cytoplasm of Escherichia coli and concluded that tRNA molecules are not able to approach the ribosome by ...
Ultrasound-induced doxorubicin release from folate-targeted and non-targeted P105 micelles: a modeling study
(De Gruyter, 2016)
The aim of this work is to study the kinetics of ultrasound (70 kHz) – using a kinetic model that takes into account cavitation events and drug re-encapsulation upon the cessation of the acoustic field. The simulation ...
Identification of the Uncertainty Structure to Estimate the Acoustic Release of Chemotherapeutics From Polymeric Micelles
(IEEE, 2017)
This paper estimates the acoustic drug release from micelles after accurately identifying the underlying statistical noise characteristics in experimental data. The drug release is measured as a change in fluorescence as ...
Investigating the Release Mechanism of Calcein from eLiposomes at Higher Temperatures
(American Scientific Publishers, 2014)
Numerous nanocarriers are currently being investigated as drug delivery vehicles for transporting chemotherapeutics to cancer cells. Our research group has recently synthesized a new generation of echogenic liposomes based ...
Novel algorithms for accurate DNA base-calling
(Scientific Research Publishing, 2013)
The ability to decipher the genetic code of different species would lead to significant future scientific achievements in important areas, including medicine and agriculture. The importance of DNA sequencing necessitated ...