Browsing Department of Chemical and Biological Engineering by Subject "Chemotherapy"
Now showing items 1-10 of 10
-
Anti-cancer Drug Delivery Using Metal Organic Frameworks (MOFs)
(Bentham Science Publishers, 2017)Cancer is the uncontrolled growth of cells in the body and is considered as one of the major causes of death globally. There are several cytotoxic chemotherapeutic agents used to treat cancer including methotrexate, ... -
Drug Delivery Systems Based on Polymeric Micelles and Ultrasound: A Review
(Bentham Science Publishers, 2016)Anti-neoplastic drugs used for cancer treatment often produce damage to healthy cells, leading to severe side effects in patients undergoing chemotherapy. The encapsulation of these agents in nanoparticles reduces the ... -
Factors Affecting the Acoustic In Vitro Release of Calcein from PEGylated Liposomes
(American Scientific Publishers, 2019)Typical methods used in cancer treatment, including chemotherapy, are debilitating because of the various adverse side effects experienced by cancer patients. The free drug injected into the patient at given doses affects ... -
Improving the Efficacy of Anticancer Drugs via Encapsulation and Acoustic Release
(Bentham Science Publishers, 2018)Conventional chemotherapeutics lack the specificity and controllability, thus may poison healthy cells while attempting to kill cancerous ones. Newly developed nano-drug delivery systems have shown promise in delivering ... -
Modeling and Bias-Robust Estimation of the Acoustic Release of Chemotherapeutics from Liposomes
(American Scientific Publishers, 2019)This paper models the acoustic drug release of chemotherapeutics from liposomes using a kinetic model that accounts for systematic biases affecting the drug delivery process. An optimal stochastic filter is then proposed ... -
Modeling the Effects of Chemotherapy and Immunotherapy on Tumor Growth
(American Scientific Publishers, 2021)Mathematical modeling has been used to simulate the interaction of chemotherapy and immunotherapy drugs intervention with the dynamics of tumor cells growth. This work studies the interaction of cells in the immune system, ... -
Photo-Induced Drug Release from Polymeric Micelles and Liposomes: Phototriggering Mechanisms in Drug-Delivery Systems
(MDPI, 2022)Chemotherapeutic drugs are highly effective in treating cancer. However, the side effects associated with this treatment lower the quality of life of cancer patients. Smart nanocarriers are able to encapsulate these drugs ... -
Predicting the Release of Chemotherapeutics From the Core of Polymeric Micelles Using Ultrasound
(IEEE Explore, 2015)In this paper, the estimation of acoustic drug release from micelles is addressed. The release is measured as a decrease in fluorescence once ultrasound is applied. Initially, a Kalman filter is used to fuse the drug ... -
Ultrasonic-Activated Micellar Drug Delivery for Cancer Treatment
(Wiley InterSciences, 2008)The use of nanoparticles and ultrasound in medicine continues to evolve. Great strides have been made in the areas of producing micelles, nanoemulsions, and solid nanoparticles that can be used in drug delivery. An effective ... -
Ultrasound-responsive Nanocarriers in Cancer Treatment: a review
(American Chemical Society, 2021)The safe and effective delivery of anticancer agents to diseased tissues is one of the significant challenges in cancer therapy. Conventional anticancer agents are generally cytotoxins with poor pharmacokinetics and ...
